SCHEMBL19783707

SCHEMBL19783707

COc1cnc2c(-c3nc4cc(F)c(OCC(C)OC(=O)Nc5ccc(C(N)=O)nc5)cc4s3)cc(C)cc2n1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395421 1.00 F2RL3 (0.70) F2RL3
SCHEMBL31113572 1.00 F2RL3 (0.70) F2RL3
SCHEMBL21379667 0.94 F2RL3 (0.70) F2RL3
SCHEMBL19783092 0.94 F2RL3 (0.70) F2RL3
SCHEMBL21395688 0.93 F2RL3 (0.71) F2RL3
SCHEMBL31113567 0.93 F2RL3 (0.71) F2RL3
SCHEMBL21395975 0.93 F2RL3 (0.64) F2RL3
SCHEMBL31113873 0.93 F2RL3 (0.64) F2RL3
SCHEMBL21395868 0.92 F2RL3 (0.69) F2RL3
SCHEMBL31113744 0.92 F2RL3 (0.69) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed