SCHEMBL19783725

SCHEMBL19783725

COCc1cnc2c(-c3nc4c(C)c(C)c(Cl)cc4s3)cc(C)cc2n1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 11/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395716 0.87 F2RL3 (0.56) F2RL3
SCHEMBL30187693 0.87 F2RL3 (0.56) F2RL3
SCHEMBL21379677 0.87 F2RL3 (0.54) F2RL3
SCHEMBL23462892 0.86 F2RL3 (0.51) F2RL3
SCHEMBL21395893 0.85 F2RL3 (0.56) F2RL3
SCHEMBL30187611 0.85 F2RL3 (0.69) F2RL3
SCHEMBL19783128 0.85 F2RL3 (0.69) F2RL3
SCHEMBL30187557 0.85 F2RL3 (0.56) F2RL3
SCHEMBL19783479 0.85 F2RL3 (0.51) F2RL3
SCHEMBL30187627 0.85 F2RL3 (0.51) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed