SCHEMBL19783748

SCHEMBL19783748

CNC(=O)c1cnc2c(-c3nc4cc(F)c(OCC(C)OC(=O)Nc5cnc(C)nc5)cc4s3)cc(C)cc2n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31113491 0.89 F2RL3 (0.56) F2RL3
SCHEMBL19783743 0.89 F2RL3 (0.56) F2RL3
SCHEMBL21395413 0.89 F2RL3 (0.56) F2RL3
SCHEMBL21395455 0.89 F2RL3 (0.70) F2RL3
SCHEMBL31113782 0.89 F2RL3 (0.70) F2RL3
SCHEMBL21396021 0.87 F2RL3 (0.61) F2RL3
SCHEMBL31114100 0.87 F2RL3 (0.61) F2RL3
SCHEMBL21395688 0.87 F2RL3 (0.71) F2RL3
SCHEMBL31113567 0.87 F2RL3 (0.71) F2RL3
SCHEMBL21396029 0.85 F2RL3 (0.60) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013774-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed