SCHEMBL1978375

SCHEMBL1978375

c1cc2cc3ccc4ccc5ccc6cc7cccc8c(c1)c2c1c3c4c5c6c1c78

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.71
ERBB2 P04626 1/20 0.71
FYN P06241 1/20 0.71
MAOA P21397 1/20 0.71
ACHE P22303 1/20 0.71
AHR P35869 1/20 0.71
ALDH1A1 P00352 8/20 0.67
HSD17B10 Q99714 7/20 0.67
HPGD P15428 5/20 0.67
THRB P10828 1/20 0.67
TSHR P16473 5/20 0.50
CYP1B1 Q16678 3/20 0.50
CYP3A4 P08684 3/20 0.50
CYP1A1 P04798 2/20 0.50
TDP1 Q9NUW8 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HIF1A Q16665 2/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21821355 0.95 CYP1A2 (0.72) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL30875854 0.95 CYP1A2 (0.72) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4846712 0.95 CYP1A2 (0.72) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4852697 0.95 CYP1A2 (0.72) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5474157 0.95 CYP1A2 (0.72) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4845221 0.95 CYP1A2 (0.72) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5474216 0.95 CYP1A2 (0.72) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4853629 0.95 CYP1A2 (0.72) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4850134 0.95 CYP1A2 (0.64) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4850514 0.93 CYP1A2 (0.69) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2260035-B1 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2014-08-20 EP claimed
US-20110149393-A1 Polycyclic Organic Compounds, Polarizing Elements and Method of Production Thereof Crysoptic KK (JP) 2011-06-23 US claimed
EP-2260035-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2010-12-15 EP claimed
US-20100071717-A1 METHOD AND APPARATUS FOR CLEANING VEHICLES R. LEWIS TECHNOLOGIES, INC. (US) 2010-03-25 US claimed
WO-2009109781-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2009-09-11 WO claimed
WO-2006135453-A1 METHOD AND APPARATUS FOR CLEANING VEHICLES R. LEWIS TECHNOLOGIES, INC. (US) 2006-12-21 WO claimed
EP-2260035-B1 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX KK (JP) 2014-08-20 EP disclosed
US-20120222794-A1 TRANSFER SUBSTRATE AND METHOD FOR FABRICATING ORGANIC ELECTROLUMINESCENT ELEMENT SONY CORPORATION (JP) 2012-09-06 US disclosed
US-8207088-B2 Transfer substrate and method for fabricating organic electroluminescent element SONY CORPORATION (JP) 2012-06-26 US disclosed
US-20110149393-A1 Polycyclic Organic Compounds, Polarizing Elements and Method of Production Thereof Crysoptic KK (JP) 2011-06-23 US disclosed
EP-2260035-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2010-12-15 EP disclosed
US-20100071717-A1 METHOD AND APPARATUS FOR CLEANING VEHICLES R. LEWIS TECHNOLOGIES, INC. (US) 2010-03-25 US disclosed
WO-2009109781-A2 POLYCYCLIC ORGANIC COMPOUNDS, POLARIZING ELEMENTS AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2009-09-11 WO disclosed
US-7470290-B2 Hydroscopic polymer gels for easier cleaning THE CLOROX COMPANY (US) 2008-12-30 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 US disclosed
US-20050245428-A1 Hydroscopic polymer gels for easier cleaning RODRIGUES KLIN A 2005-11-03 US disclosed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US disclosed
WO-2005040303-A1 AGGREGATE ORGANIC LIGHT EMITTING DIODE DEVICES EASTMAN KODAK COMPANY (US) 2005-05-06 WO disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110149393-A1 Polycyclic Organic Compounds, Polarizing Elements and Method of Production Thereof CCNB1, CCNB2, CCNE2 CYP1A2 213/4885ERBB2 2194/4885FYN 2260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.