Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328613 | 0.87 | FGFR4 (0.55) | FGFR4 | |
| SCHEMBL21000258 | 0.87 | FGFR4 (0.75) | FGFR4 | |
| SCHEMBL29597029 | 0.87 | FGFR4 (0.75) | FGFR4 | |
| SCHEMBL19783874 | 0.87 | FGFR4 (0.75) | FGFR4 | |
| SCHEMBL22023347 | 0.87 | FGFR4 (0.75) | FGFR4 | |
| SCHEMBL20971315 | 0.85 | FGFR4 (0.64) | FGFR4 | |
| SCHEMBL22080154 | 0.84 | FGFR4 (0.56) | FGFR4 | |
| SCHEMBL27053883 | 0.82 | FGFR4 (0.58) | FGFR4 | |
| SCHEMBL23328597 | 0.82 | FGFR4 (0.55) | FGFR4 | |
| SCHEMBL21000343 | 0.82 | FGFR4 (0.87) | FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663285-A1 | FORMYLPYRIDINE DERIVATIVE HAVING FGFR4 INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2020-06-10 | — | — | EP | disclosed |
| WO-2018010514-A1 | HETEROCYCLIC COMPOUND USED AS FGFR INHIBITOR | 南京天印健华医药科技有限公司 | 2018-01-18 | — | — | WO | disclosed |