Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 4/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655019 | 0.85 | HDAC1 (0.44) | HDAC1HDAC2HDAC6CYP1A2GAA | |
| SCHEMBL8887438 | 0.80 | HDAC1 (0.40) | HDAC1HDAC2HDAC6KDM5ADNM1 | |
| SCHEMBL15055158 | 0.80 | CYP1A2 (0.53) | HDAC1HDAC2HDAC6CYP1A2GAA | |
| SCHEMBL27643241 | 0.80 | CYP1A2 (0.53) | HDAC1HDAC2HDAC6CYP1A2GAA | |
| SCHEMBL26648449 | 0.80 | CYP1A2 (0.53) | HDAC1HDAC2HDAC6CYP1A2GAA | |
| SCHEMBL29285429 | 0.80 | CA14 (0.47) | HDAC1HDAC2HDAC6ALOX5CYP1A2 | |
| SCHEMBL7344626 | 0.79 | CYP1A2 (0.40) | HDAC1HDAC2HDAC6CYP1A2GAA | |
| SCHEMBL21937996 | 0.79 | CA14 (0.41) | HDAC1HDAC2HDAC6KDM5AKDM4C | |
| SCHEMBL27643221 | 0.78 | CYP1A2 (0.55) | CYP1A2GAAALDH1A1TDP1ALOX15 | |
| SCHEMBL1272960 | 0.78 | CA14 (0.49) | HDAC1HDAC2HDAC6ALOX5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369848-A1 | Conjugation Method for Carrier-Linked Prodrugs | Ascendls Pharma A/S (DK) | 2021-12-02 | — | — | US | disclosed |
| WO-2018011266-A1 | CONJUGATION METHOD FOR CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369848-A1 | Conjugation Method for Carrier-Linked Prodrugs | UGT2B7, SLC10A1, UGT1A6 | HDAC1 716/4885HDAC2 753/4885HDAC6 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.