SCHEMBL19784531

SCHEMBL19784531

O=C(Cl)OC1CCCCC1Oc1cc2sc(Cl)nc2cc1F

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19784528 1.00 F2RL3 (0.45) F2RL3
SCHEMBL19784769 0.95 F2RL3 (0.44) F2RL3
SCHEMBL19784770 0.95 F2RL3 (0.44) F2RL3
SCHEMBL21942184 0.95 F2RL3 (0.44) F2RL3
SCHEMBL21407921 0.95 F2RL3 (0.44) F2RL3
SCHEMBL22274539 0.89 F2RL3 (0.45) F2RL3
SCHEMBL22274540 0.89 F2RL3 (0.45) F2RL3
SCHEMBL21874607 0.89 F2RL3 (0.45) F2RL3
SCHEMBL21407949 0.80 F2RL3 (0.64) F2RL3
SCHEMBL19784762 0.80 F2RL3 (0.64) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484881-B1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2020-04-29 EP disclosed
WO-2018013770-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed