SCHEMBL19784735

SCHEMBL19784735

O=C(Nc1cnc(OCCO)nc1)OC1CCC1Oc1cc2sc(Cl)nc2cc1F

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19784736 1.00 F2RL3 (0.68) F2RL3
SCHEMBL21942183 1.00 F2RL3 (0.68) F2RL3
SCHEMBL19784771 0.88 F2RL3 (0.58) F2RL3
SCHEMBL21942185 0.82 F2RL3 (1.00) F2RL3
SCHEMBL21941300 0.82 F2RL3 (1.00) F2RL3
SCHEMBL19784278 0.82 F2RL3 (1.00) F2RL3
SCHEMBL21424394 0.82 F2RL3 (1.00) F2RL3
SCHEMBL21424395 0.81 F2RL3 (1.00) F2RL3
SCHEMBL21424332 0.81 F2RL3 (1.00) F2RL3
SCHEMBL21424398 0.79 F2RL3 (1.00) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013770-A1 BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-01-18 WO disclosed