SCHEMBL19785387

SCHEMBL19785387

Cc1cc(Cl)c(-c2cc(C)c(C)cc2Cl)cc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.50
MAPK1 P28482 2/20 0.50
CD44 P16070 1/20 0.39
CYP3A4 P08684 3/20 0.36
CHRM1 P11229 1/20 0.35
ALOX15 P16050 1/20 0.35
MAOA P21397 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
HTR2B P41595 1/20 0.35
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
HSD11B1 P28845 1/20 0.33
PLA2G7 Q13093 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12107994 0.84 AHR (0.56) AHRMAPK1CD44CYP3A4CHRM1
SCHEMBL172591 0.82 CD44 (0.45) AHRMAPK1CD44CYP3A4CHRM1
SCHEMBL13176877 0.78 CD44 (0.50) AHRMAPK1CD44CYP3A4CHRM1
SCHEMBL27142057 0.77 CYP2A6 (0.50) MAPK1ESR1ESR2CYP1A1CYP1A2
SCHEMBL10524409 0.77 CD44 (0.56) AHRMAPK1CD44CYP3A4ALOX15
SCHEMBL2219302 0.76 CD44 (0.55) MAPK1CD44CYP3A4CHRM1ALOX15
SCHEMBL120848 0.74 CD44 (0.61) CD44CYP3A4CHRM1ALOX15MAOA
SCHEMBL1134711 0.73 CYP3A4 (0.41) MAPK1CYP3A4CHRM1ALOX15MAOA
SCHEMBL20831934 0.72 CA12 (0.46) CYP1A1CYP1A2PLA2G7TSHR
Water SCHEMBL29026586 0.72 CD44 (0.58) CD44CYP3A4CHRM1ALOX15MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10246415-B2 Process for preparing carbazoles DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-02 US disclosed
WO-2018013067-A1 PROCESS FOR PREPARING CARBAZOLES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10246415-B2 Process for preparing carbazoles DCLK2, DCLK1, PDCD2L AHR 138/4885MAPK1 1454/4885CD44 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.