⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20362930 | 0.82 | — | — | |
| SCHEMBL13848591 | 0.75 | MEN1 (0.41) | — | |
| SCHEMBL2616804 | 0.75 | TLR8 (0.33) | — | |
| SCHEMBL30665022 | 0.72 | KCNH2 (0.38) | — | |
| SCHEMBL13566391 | 0.72 | KCNH2 (0.38) | — | |
| SCHEMBL13566370 | 0.70 | — | — | |
| SCHEMBL6987094 | 0.69 | CCNE2 (0.33) | — | |
| SCHEMBL9317078 | 0.69 | — | — | |
| SCHEMBL6987092 | 0.69 | CCNE2 (0.33) | — | |
| SCHEMBL6504654 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255044-B1 | DIAZA-BENZOFLUORANTHRENE COMPOUNDS | HARBIN PHARMACEUTICAL GROUP CO LTD GENERAL PHARMACEUTICAL FACTORY (CN) | 2020-04-01 | — | — | EP | disclosed |
| US-20180016270-A1 | DIAZA-BENZOFLUORANTHRENE COMPOUNDS | HARBIN PHARMACEUTICAL GROUP CO., LTD. GENERAL PHARMACEUTICAL FACTORY (CN) | 2018-01-18 | — | — | US | disclosed |