SCHEMBL19785475

SCHEMBL19785475

CC(C)NC(=O)C(C(C)C)C(C)C=O

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
CA9 Q16790 1/20 0.32
MEN1 O00255 1/20 0.31
FAAH O00519 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5018136 0.81 CA1 (0.40) TSHRALDH1A1GAACA12CA1
SCHEMBL142029 0.70
SCHEMBL18626021 0.68 CA12 (0.31) TSHRCA12CA1CA2MMP1
Hydrochloric Acid SCHEMBL28967104 0.68 CA12 (0.42) TSHRALDH1A1GAACA12CA1
SCHEMBL18909885 0.66 CA12 (0.40) TSHRALDH1A1GAACA12CA1
SCHEMBL18909884 0.66 CA12 (0.40) TSHRALDH1A1GAACA12CA1
SCHEMBL12724859 0.66 CA12 (0.40) TSHRALDH1A1GAACA12CA1
SCHEMBL23559895 0.64 CA1 (0.31) ALDH1A1CA1CA2
SCHEMBL12545610 0.64 CA12 (0.39) TSHRALDH1A1GAACA12CA1
SCHEMBL19000042 0.64 CA12 (0.39) TSHRALDH1A1GAACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180016396-A1 POLY(ASPARTIC ACID) DERIVED CO-POLYMERS FOR A CONTROLLED RELEASE OF PERFUMING INGREDIENTS FIRMENICH SA (CH) 2018-01-18 US disclosed