Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 4/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219154 | 0.93 | KMT2A (0.42) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL1976602 | 0.92 | PPARA (0.42) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL13053335 | 0.92 | PPARA (0.42) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL17183914 | 0.88 | KMT2A (0.41) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL12024363 | 0.86 | KLK7 (0.41) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL12024362 | 0.86 | KLK7 (0.41) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL1219509 | 0.85 | KMT2A (0.43) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL13053328 | 0.84 | KMT2A (0.42) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL16510414 | 0.84 | KLK7 (0.42) | PPARAKMT2AL3MBTL1KLK7KLK5 | |
| SCHEMBL12023829 | 0.84 | KLK7 (0.42) | PPARAKMT2AL3MBTL1KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8834841-B2 | Imaging agents | EMORY UNIVERSITY (US) | 2014-09-16 | — | — | US | disclosed |
| US-20130225828-A1 | IMAGING AGENTS | EMORY UNIVERSITY (US) | 2013-08-29 | — | — | US | disclosed |
| US-8435493-B2 | Imaging agents | EMORY UNIVERSITY (US) | 2013-05-07 | — | — | US | disclosed |
| US-20110144483-A1 | IMAGING AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-16 | — | — | US | disclosed |
| US-7837982-B2 | Imaging agents | EMORY UNIVERSITY (US) | 2010-11-23 | — | — | US | disclosed |
| US-20070082879-A1 | Imaging Agents | EMORY UNIVERSITY (US) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144483-A1 | IMAGING AGENTS | SLC7A1, SSTR1, SSTR3 | PPARA 4740/4885KMT2A 2212/4885L3MBTL1 848/4885 |
| US-20070082879-A1 | Imaging Agents | SLC7A1, SSTR1, SSTR3 | PPARA 4740/4885KMT2A 2212/4885L3MBTL1 848/4885 |
| US-20130225828-A1 | IMAGING AGENTS | SLC7A1, SSTR1, SSTR3 | PPARA 4741/4885KMT2A 2209/4885L3MBTL1 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.