Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824160 | 1.00 | PDK2 (0.55) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL30463510 | 1.00 | PDK2 (0.55) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL19164437 | 0.98 | PDK2 (0.54) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL19164438 | 0.98 | PDK2 (0.54) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL24730387 | 0.95 | PDK2 (0.51) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL761313 | 0.90 | PDK2 (0.47) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL490501 | 0.90 | PDK2 (0.47) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL30480901 | 0.90 | PDK2 (0.49) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL25604177 | 0.90 | PDK2 (0.49) | PDK2THRBTDP1OPRM1OPRD1 | |
| SCHEMBL19164107 | 0.89 | PDK2 (0.46) | PDK2THRBTDP1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10056559-B2 | Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-08-21 | — | — | US | disclosed |
| US-20180175295-A1 | SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE | SEMICONDUCTOR ENERGY LAB (JP) | 2018-06-21 | — | — | US | disclosed |
| US-20180175295-A1 | SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE | SEMICONDUCTOR ENERGY LAB (JP) | 2018-06-21 | — | — | US | disclosed |
| US-20180175295-A1 | SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE | SEMICONDUCTOR ENERGY LAB (JP) | 2018-06-21 | — | — | US | disclosed |
| US-9899602-B2 | Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-02-20 | — | — | US | disclosed |
| US-9899602-B2 | Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-02-20 | — | — | US | disclosed |
| US-9899602-B2 | Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-02-20 | — | — | US | disclosed |
| US-20170125679-A1 | SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE | SEMICONDUCTOR ENERGY LAB (JP) | 2017-05-04 | — | — | US | disclosed |
| US-20170125679-A1 | SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE | SEMICONDUCTOR ENERGY LAB (JP) | 2017-05-04 | — | — | US | disclosed |
| US-20170125679-A1 | SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE | SEMICONDUCTOR ENERGY LAB (JP) | 2017-05-04 | — | — | US | disclosed |
| EP-0968175-A1 | SPIRO COMPOUNDS AND THE USE THEREOF | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-01-05 | — | — | EP | disclosed |
| EP-0935691-A1 | OPTICAL BRIGHTENING AGENT | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-08-18 | — | — | EP | disclosed |
| WO-1999040655-A1 | USE OF SPIRO COMPOUNDS AS LASER DYES | AXIVA GMBH (DE) | 1999-08-12 | — | — | WO | disclosed |
| US-5840217-A | LIGHT-EMITTING, CHARGE-TRANSPORT, CHARGE-INJECTION MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042655-A1 | SPIRO COMPOUNDS AND THE USE THEREOF | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998018996-A1 | OPTICAL BRIGHTENING AGENT | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-05-07 | — | — | WO | disclosed |
| EP-0768563-A1 | Use of spiro compounds as active materials for non-linear optic | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5621131-A | Conjugated polymers having spiro centers and their use as electroluminescence materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| EP-0707020-A2 | Conjugated polymers with a spiro atom and their use as electroluminescent materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-17 | — | — | EP | disclosed |
| EP-0676461-A2 | Spiro compounds and their application as electroluminescence materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170125679-A1 | SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE | GRK1, PTGER2, PTGER1 | PDK2 960/4885THRB 721/4885TDP1 3612/4885 |
| US-20180175295-A1 | SPIROFLUORENE DERIVATIVE, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE | GRK1, PTGER2, PTGER1 | PDK2 960/4885THRB 721/4885TDP1 3612/4885 |
| US-10056559-B2 | Spirofluorene derivative, material for light-emitting element, light-emitting element, light-emitting device, and electronic device | GRK1, PTGER2, PTGER1 | PDK2 960/4885THRB 721/4885TDP1 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.