Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 19/20 | 0.68 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.59 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12598632 | 0.85 | RPS6KA2 (0.73) | RPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL1979125 | 0.82 | RPS6KA2 (0.68) | RPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL1978192 | 0.81 | RPS6KA2 (1.00) | RPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL14891752 | 0.76 | RPS6KA2 (1.00) | RPS6KA2RPS6KA3 | |
| SCHEMBL12598248 | 0.76 | RPS6KA2 (1.00) | RPS6KA2RPS6KA3 | |
| SCHEMBL12598735 | 0.76 | RPS6KA2 (1.00) | RPS6KA2RPS6KA3 | |
| SCHEMBL12598245 | 0.76 | RPS6KA2 (1.00) | RPS6KA2RPS6KA3 | |
| SCHEMBL14907208 | 0.74 | RPS6KA2 (1.00) | RPS6KA2RPS6KA3MAPKAPK2 | |
| SCHEMBL12598758 | 0.74 | RPS6KA2 (1.00) | RPS6KA2RPS6KA3 | |
| SCHEMBL12598764 | 0.74 | RPS6KA2 (1.00) | RPS6KA2RPS6KA3MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509980-A1 | HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE | Boehringer Ingelheim International GmbH (DE) | 2012-10-17 | — | — | EP | claimed |
| WO-2011071716-A1 | HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | WO | claimed |