⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20664444 | 0.78 | — | — | |
| SCHEMBL15547358 | 0.73 | FUCA1 (0.31) | — | |
| SCHEMBL18776588 | 0.72 | — | — | |
| SCHEMBL26049791 | 0.71 | — | — | |
| SCHEMBL17652478 | 0.66 | — | — | |
| SCHEMBL23712049 | 0.65 | SLC6A2 (0.33) | — | |
| SCHEMBL21184292 | 0.65 | TSHR (0.37) | — | |
| SCHEMBL9069116 | 0.63 | GANAB (0.30) | — | |
| SCHEMBL23656010 | 0.63 | — | — | |
| SCHEMBL23711674 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013761-A1 | CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE TREATMENT OF RIBOSOMAL DISORDERS AND RIBOSOMAPATHIES | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2018-01-18 | — | — | WO | disclosed |