SCHEMBL19786387

SCHEMBL19786387

CCCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCNC(=O)CC[C@H](NC(=O)CCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.77

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.77
NOD1 Q9Y239 9/20 0.55
CCKAR P32238 3/20 0.47
CCKBR P32239 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19786598 0.99 GLP1R (0.76) GLP1RNOD1CCKARCCKBR
SCHEMBL19786734 0.99 GLP1R (0.76) GLP1RNOD1CCKARCCKBR
SCHEMBL18551952 0.99 GLP1R (0.76) GLP1RNOD1CCKARCCKBR
SCHEMBL18552229 0.99 GLP1R (0.76) GLP1RNOD1CCKARCCKBR
SCHEMBL23253771 0.99 GLP1R (0.79) GLP1RNOD1CCKARCCKBR
SCHEMBL8258329 0.99 GLP1R (0.79) GLP1RNOD1CCKARCCKBR
SCHEMBL29322838 0.99 GLP1R (0.79) GLP1RNOD1CCKARCCKBR
SCHEMBL24838647 0.99 GLP1R (0.79) GLP1RNOD1CCKARCCKBR
SCHEMBL18893454 0.99 GLP1R (0.79) GLP1RNOD1CCKARCCKBR
SCHEMBL29323009 0.99 GLP1R (0.79) GLP1RNOD1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180044394-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE NOVO NORDISK AS (DK) 2018-02-15 US disclosed
US-20180016319-A1 Acylated Glucagon Analogues NOVO NORDISK AS (DK) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044394-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE GLP1R, GIPR, GCGR GLP1R 1/4885NOD1 1398/4885CCKAR 24/4885
US-20180016319-A1 Acylated Glucagon Analogues GLP1R, GCG, IAPP GLP1R 1/4885NOD1 2294/4885CCKAR 120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.