Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | BCHE | P06276 | 9/20 | 0.56 |
| ▸ | ACHE | P22303 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15323753 | 1.00 | CA12 (0.65) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL2380754 | 1.00 | CA12 (0.65) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL2380759 | 1.00 | CA12 (0.65) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL2379525 | 0.99 | CA12 (0.66) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL2379521 | 0.99 | CA12 (0.66) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL2381206 | 0.95 | CA12 (0.67) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL2381388 | 0.95 | CA12 (0.67) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL2379548 | 0.91 | CA12 (0.65) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL2378787 | 0.91 | CA12 (0.65) | CA12CA9BCHEACHEHSD17B10 | |
| SCHEMBL16374022 | 0.90 | CA12 (0.65) | CA12CA9BCHEACHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013999-A1 | NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS | AM CHEMICALS LLC (US) | 2018-01-18 | — | — | WO | disclosed |