Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | HCK | P08631 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30417764 | 1.00 | PIK3CD (0.42) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL21457948 | 0.88 | PIK3CD (0.43) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL21457950 | 0.88 | PIK3CD (0.43) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL34460129 | 0.86 | HDAC1 (0.45) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL1056190 | 0.85 | CYP2A6 (0.51) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL14865810 | 0.85 | PIK3CD (0.44) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL1057492 | 0.85 | PIK3CD (0.41) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL30418492 | 0.85 | PIK3CD (0.41) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL30418960 | 0.85 | PIK3CD (0.46) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL1057494 | 0.85 | PIK3CD (0.41) | PIK3CDABL1EGFRHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484842-B1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2023-05-03 | — | — | EP | disclosed |
| WO-2018013943-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-18 | — | — | WO | disclosed |