Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730562 | 1.00 | MAPK14 (0.31) | MAPK14NAAAACSS2 | |
| SCHEMBL2718961 | 1.00 | MAPK14 (0.31) | MAPK14NAAAACSS2 | |
| SCHEMBL2730563 | 1.00 | MAPK14 (0.31) | MAPK14NAAAACSS2 | |
| SCHEMBL17549875 | 1.00 | MAPK14 (0.31) | MAPK14NAAAACSS2 | |
| SCHEMBL19787839 | 0.81 | SCD (0.31) | — | |
| SCHEMBL2717748 | 0.81 | TYK2 (0.35) | MAPK14NAAA | |
| SCHEMBL2718963 | 0.79 | — | — | |
| SCHEMBL2718966 | 0.79 | — | — | |
| SCHEMBL3777197 | 0.74 | PIK3CD (0.39) | MAPK14 | |
| SCHEMBL2717040 | 0.74 | PIK3CD (0.39) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873704-B2 | Heterocyclic compounds and their uses | AMGEN INC. (US) | 2018-01-23 | — | — | US | disclosed |