Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.72 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.72 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | FABP3 | P05413 | 1/20 | 0.68 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.62 |
| ▸ | SELP | P16109 | 1/20 | 0.60 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984104 | 0.95 | LPAR3 (0.79) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL21249160 | 0.95 | LPAR3 (0.79) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL12195367 | 0.95 | LPAR3 (0.79) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL28671483 | 0.95 | LPAR3 (0.79) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL17232172 | 0.91 | LPAR3 (0.85) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL23225826 | 0.88 | SELP (0.76) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL40543 | 0.88 | SELP (0.76) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL21641458 | 0.88 | SELP (0.76) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL2622733 | 0.88 | SELP (0.76) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 | |
| SCHEMBL40542 | 0.88 | SELP (0.76) | LPAR3LPAR1ENPP2SMN1; SMN2FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872870-B2 | Multifunctional micellar nanoparticle-based drug and targeting agent system | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2018-01-23 | — | — | US | disclosed |