Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 16/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.54 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911052 | 1.00 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL20910851 | 0.90 | FOLH1 (0.66) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL24123152 | 0.89 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL9912229 | 0.89 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18253629 | 0.89 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18538620 | 0.87 | FOLH1 (0.48) | FOLH1 | |
| SCHEMBL26758628 | 0.87 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL12118207 | 0.84 | PRMT1 (0.45) | FOLH1 | |
| SCHEMBL19359999 | 0.84 | FOLH1 (0.65) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19360024 | 0.84 | FOLH1 (0.83) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872913-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER INC. (US) | 2018-01-23 | — | — | US | disclosed |