Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 14/20 | 0.85 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.59 |
| ▸ | RPS6KA2 | Q15349 | 15/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088114 | 0.88 | RPS6KA3 (0.67) | RPS6KA3MAPKAPK2RPS6KA2 | |
| SCHEMBL4831402 | 0.81 | RPS6KA3 (0.59) | RPS6KA3MAPKAPK2RPS6KA2 | |
| SCHEMBL3086735 | 0.80 | RPS6KA3 (0.58) | RPS6KA3MAPKAPK2RPS6KA2 | |
| SCHEMBL19252882 | 0.80 | RPS6KA3 (0.56) | RPS6KA3MAPKAPK2RPS6KA2 | |
| SCHEMBL1980016 | 0.80 | RPS6KA3 (0.79) | RPS6KA3MAPKAPK2RPS6KA2 | |
| SCHEMBL3084607 | 0.79 | RPS6KA2 (0.88) | RPS6KA3MAPKAPK2RPS6KA2 | |
| SCHEMBL16100366 | 0.78 | RPS6KA2 (0.69) | RPS6KA3MAPKAPK2RPS6KA2 | |
| SCHEMBL1393632 | 0.78 | RPS6KA3 (0.53) | RPS6KA3MAPKAPK2RPS6KA2 | |
| SCHEMBL12598261 | 0.78 | RPS6KA2 (0.64) | RPS6KA3RPS6KA2 | |
| SCHEMBL24187362 | 0.77 | RPS6KA2 (0.56) | RPS6KA3MAPKAPK2RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509980-A1 | HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE | Boehringer Ingelheim International GmbH (DE) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071716-A1 | HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | WO | disclosed |