Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 18/20 | 0.47 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912229 | 0.84 | FOLH1 (0.68) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL18253629 | 0.84 | FOLH1 (0.68) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL24123152 | 0.84 | FOLH1 (0.68) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL20910851 | 0.82 | FOLH1 (0.66) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL26757838 | 0.82 | FOLH1 (0.58) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL13884310 | 0.80 | FOLH1 (0.40) | FOLH1ITGB3ITGA2B | |
| SCHEMBL13893519 | 0.80 | FOLH1 (0.40) | FOLH1ITGB3ITGA2B | |
| SCHEMBL26757300 | 0.79 | FOLH1 (0.65) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL14450667 | 0.79 | FOLH1 (0.40) | FOLH1NAALAD2ITGB3ITGA2B | |
| SCHEMBL18272834 | 0.79 | FOLH1 (0.40) | FOLH1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872913-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER INC. (US) | 2018-01-23 | — | — | US | disclosed |