Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | CSF1R | P07333 | 9/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789088 | 0.87 | EGFR (0.67) | EGFRHDAC1HDAC8HDAC6CSF1R | |
| SCHEMBL19789093 | 0.86 | EGFR (0.58) | EGFRHDAC1HDAC8HDAC6CSF1R | |
| SCHEMBL19789100 | 0.84 | EGFR (0.57) | EGFRHDAC1HDAC8HDAC6PDGFRB | |
| SCHEMBL19789103 | 0.84 | EGFR (0.62) | EGFRHDAC1HDAC8HDAC6CSF1R | |
| SCHEMBL19789107 | 0.83 | HDAC1 (0.53) | EGFRHDAC1HDAC8HDAC6CSF1R | |
| SCHEMBL3119399 | 0.81 | EGFR (0.79) | EGFRHDAC1HDAC8HDAC6CSF1R | |
| SCHEMBL19789095 | 0.81 | EGFR (0.58) | EGFRHDAC1HDAC8HDAC6CSF1R | |
| SCHEMBL24653822 | 0.78 | EGFR (0.60) | EGFRHDAC1HDAC8HDAC6CSF1R | |
| SCHEMBL3109912 | 0.77 | EGFR (1.00) | EGFRHDAC1HDAC8HDAC6CSF1R | |
| Hydrochloric Acid SCHEMBL6182107 | 0.75 | EGFR (0.97) | EGFRHDAC1HDAC8HDAC6CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272742-A1 | HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-01-24 | — | — | EP | disclosed |