SCHEMBL1978930

SCHEMBL1978930

O=C(O)c1ccc(F)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70493 0.81 DAO (0.67)
Hydrochloric Acid SCHEMBL3074364 0.78 DAO (0.64)
SCHEMBL29808747 0.78 DAO (0.64)
SCHEMBL28343181 0.78 DAO (0.64)
SCHEMBL28353716 0.78 DAO (0.64)
SCHEMBL19987844 0.78 DAO (0.64)
Hydrochloric Acid SCHEMBL1979156 0.78 DAO (0.64)
SCHEMBL27562112 0.78 DAO (0.64)
SCHEMBL11598753 0.78 DAO (0.64)
SCHEMBL3838638 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721688-B Intelligent flexible transparent electrode for realizing multiple switching effect and preparation method thereof 广州中国科学院先进技术研究所 2021-05-25 CN claimed
EP-2200440-B1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS CRESTONE INC (US) 2017-07-19 EP claimed
EP-1680124-B1 BICYCLIC [3.1.0] DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS PFIZER PROD INC (US) 2017-05-31 EP claimed
EP-2511268-B1 OXAZINE DERIVATIVE SHIONOGI & CO (JP) 2016-07-13 EP claimed
EP-2509966-B1 AMINO OXAZINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2014-10-22 EP claimed
EP-2509966-A1 AMINO OXAZINE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2012-10-17 EP claimed
CN-102652129-A Amino oxazine derivatives HOFFMANN LA ROCHE 2012-08-29 CN claimed
CN-101838271-A Bicyclic [3.1.0] derivatives as glycine transporter inhibitors PFIZER PROD INC 2010-09-22 CN claimed
EP-2200440-A1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS Crestone, Inc. (US) 2010-06-30 EP claimed
EP-1680124-A4 BICYCLIC [3.1.0] DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS PFIZER PROD INC (US) 2009-05-13 EP claimed
WO-2009015208-A1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS REPLIDYNE, INC. (US) 2009-01-29 WO claimed
JP-2007508374-A 2007-04-05 JP claimed
CN-1867338-A Bicyclic [3.1.0] derivatives as glycine transporter inhibitors PFIZER PROD INC (US) 2006-11-22 CN claimed
EP-1680124-A2 BICYCLIC [3.1.0] DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS Pfizer Products Incorporated (US) 2006-07-19 EP claimed
US-20050096375-A1 Bicyclic [3.1.0] derivatives as glycine transporter inhibitors PFIZER INC. 2005-05-05 US claimed
WO-2005037216-A2 BICYCLIC [3.1.0] DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS PFIZER PRODUCTS INC. (US) 2005-04-28 WO claimed
US-12600730-B2 Substituted cyclopenta[c]pyrroles as ABHD6 antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 2026-04-14 US disclosed
US-20250296926-A1 SELECTIVE LIGANDS FOR MODULATION OF GIRK CHANNELS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION 2025-09-25 US disclosed
US-6043379-A Processes and intermediates for preparing 2-fluorothiophene derivatives PFIZER INC. (US) 2000-03-28 US disclosed
WO-1998045282-A1 PROCESSES AND INTERMEDIATES FOR PREPARING 2-FLUOROTHIOPHENE DERIVATIVES PFIZER INC. (US) 1998-10-15 WO disclosed