Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567323 | 0.93 | CA1 (0.51) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL5694166 | 0.89 | TSHR (0.57) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL29316026 | 0.89 | TDP1 (0.59) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL29316023 | 0.89 | TDP1 (0.59) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL12725802 | 0.88 | CA1 (0.54) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL29316022 | 0.87 | TDP1 (0.58) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL16351937 | 0.87 | TDP1 (0.50) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL16351931 | 0.87 | TDP1 (0.50) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL13572524 | 0.86 | POLB (0.64) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL7102222 | 0.85 | TDP1 (0.59) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |