Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 15/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786493 | 0.81 | S1PR1 (0.64) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1567290 | 0.81 | S1PR1 (0.64) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2168010 | 0.71 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2180247 | 0.71 | S1PR1 (0.56) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1567321 | 0.71 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL1567318 | 0.71 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL21958845 | 0.70 | S1PR1 (0.61) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1568166 | 0.70 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL1568163 | 0.70 | S1PR1 (1.00) | S1PR1S1PR3 | |
| SCHEMBL27876603 | 0.69 | S1PR1 (0.80) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272736-A1 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | NOVARTIS AG (CH) | 2018-01-24 | — | — | EP | disclosed |