Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519517 | 0.95 | PDE10A (0.72) | PDE10AALDH1A1 | |
| SCHEMBL14729638 | 0.94 | PDE10A (0.70) | PDE10AALDH1A1 | |
| SCHEMBL10039435 | 0.93 | PDE10A (0.69) | PDE10AALDH1A1 | |
| SCHEMBL14729554 | 0.92 | PDE10A (0.68) | PDE10AALDH1A1 | |
| SCHEMBL18973465 | 0.91 | PDE10A (0.67) | PDE10AALDH1A1 | |
| SCHEMBL15004764 | 0.91 | PDE10A (0.69) | PDE10AALDH1A1 | |
| SCHEMBL519787 | 0.91 | PDE10A (0.69) | PDE10AALDH1A1 | |
| SCHEMBL8369707 | 0.90 | PDE10A (0.68) | PDE10AALDH1A1 | |
| SCHEMBL10039671 | 0.89 | PDE10A (0.67) | PDE10AALDH1A1 | |
| SCHEMBL15004678 | 0.89 | PDE10A (0.69) | PDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748158-B1 | RADIOLABELED COMPOUNDS AND THEIR USE AS RADIOTRACERS FOR QUANTITATIVE IMAGING OF PHOSPHODIESTERASE (PDE10A) IN MAMMALS | TAKEDA PHARMACEUTICALS CO (JP) | 2018-01-24 | — | — | EP | disclosed |