Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12180529 | 0.83 | MEN1 (0.58) | POLBMEN1KMT2ASMN1; SMN2APP | |
| SCHEMBL2106645 | 0.81 | HPGD (0.54) | LMNASMN1; SMN2HPGDACACB | |
| SCHEMBL2106643 | 0.81 | HPGD (0.54) | LMNASMN1; SMN2HPGDACACB | |
| SCHEMBL15052901 | 0.76 | HPGD (0.56) | LMNASMN1; SMN2HPGDACACB | |
| SCHEMBL17859718 | 0.75 | HPGD (0.58) | POLBKMT2ASMN1; SMN2HPGDACACB | |
| SCHEMBL31500690 | 0.74 | HPGD (0.63) | KMT2ASMN1; SMN2HPGD | |
| SCHEMBL31500691 | 0.74 | HPGD (0.63) | KMT2ASMN1; SMN2HPGD | |
| SCHEMBL27493711 | 0.74 | HPGD (0.63) | KMT2ASMN1; SMN2HPGD | |
| SCHEMBL15200213 | 0.73 | HPGD (0.59) | POLBKMT2ALMNASMN1; SMN2HPGD | |
| SCHEMBL5907838 | 0.73 | KMT2A (0.73) | POLBMEN1KMT2ASMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582709-B1 | AZOLOPYRIDIN-3-ONE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES | SANOFI SA (FR) | 2018-01-24 | — | — | EP | disclosed |