Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789991 | 0.93 | KCNH2 (0.36) | APPKCNH2CA12CA2CA9 | |
| SCHEMBL19789971 | 0.83 | APP (0.39) | APPNPC1MAPTMEN1ALDH1A1 | |
| SCHEMBL19789980 | 0.83 | APP (0.39) | APPNPC1MAPTMEN1ALDH1A1 | |
| SCHEMBL24390823 | 0.79 | APP (0.41) | APPNPC1MAPTMEN1ALDH1A1 | |
| SCHEMBL19789973 | 0.79 | APP (0.41) | APPNPC1MAPTMEN1ALDH1A1 | |
| SCHEMBL19789800 | 0.79 | APP (0.41) | APPNPC1MAPTMEN1ALDH1A1 | |
| SCHEMBL19789977 | 0.79 | APP (0.67) | APPNPC1MAPTMEN1ALDH1A1 | |
| SCHEMBL22225396 | 0.79 | APP (0.67) | APPNPC1MAPTMEN1ALDH1A1 | |
| SCHEMBL19790008 | 0.76 | KCNH2 (0.41) | APPNPC1MAPTMEN1ALDH1A1 | |
| SCHEMBL19790006 | 0.75 | KCNH2 (0.34) | KCNH2CA12CA2CA9FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794816-B1 | LIQUID CRYSTAL MEDIUM AND HIGH FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |