Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 15/20 | 0.36 |
| ▸ | LONP1 | P36776 | 8/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.34 |
| ▸ | PSMB11 | A5LHX3 | 6/20 | 0.34 |
| ▸ | PSMA7 | O14818 | 6/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.34 |
| ▸ | PSMA1 | P25786 | 6/20 | 0.34 |
| ▸ | PSMA2 | P25787 | 6/20 | 0.34 |
| ▸ | PSMA3 | P25788 | 6/20 | 0.34 |
| ▸ | PSMA4 | P25789 | 6/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 6/20 | 0.34 |
| ▸ | PSMA5 | P28066 | 6/20 | 0.34 |
| ▸ | PSMB4 | P28070 | 6/20 | 0.34 |
| ▸ | PSMB6 | P28072 | 6/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 6/20 | 0.34 |
| ▸ | PSMB3 | P49720 | 6/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.34 |
| ▸ | PSMA6 | P60900 | 6/20 | 0.34 |
| ▸ | PSMA8 | Q8TAA3 | 6/20 | 0.34 |
| ▸ | PSMB7 | Q99436 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19790128 | 0.78 | PSMB5 (0.43) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL19790134 | 0.75 | PSMB5 (0.43) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL19790172 | 0.73 | PSMB5 (0.39) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL2503846 | 0.69 | PSMB5 (0.52) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL19790171 | 0.65 | PSMB5 (0.41) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL19790168 | 0.64 | PSMB5 (0.42) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL19790165 | 0.64 | PSMB5 (0.46) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL19790233 | 0.64 | PSMB5 (0.43) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL19790236 | 0.63 | PSMB5 (0.45) | PSMB5LONP1PSMB8PSMB11PSMA7 | |
| SCHEMBL19790235 | 0.62 | PSMB5 (0.43) | PSMB5LONP1PSMB8PSMB11PSMA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552216-B1 | DERIVATIVES OF 1-AMINO-2-CYCLOPROPYLETHYLBORONIC ACID | MILLENNIUM PHARM INC (US) | 2018-01-24 | — | — | EP | disclosed |