Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 13/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.45 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.45 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.45 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.45 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.45 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.45 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.45 |
| ▸ | PSMB3 | P49720 | 4/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.45 |
| ▸ | PSMA6 | P60900 | 4/20 | 0.45 |
| ▸ | PSMA8 | Q8TAA3 | 4/20 | 0.45 |
| ▸ | PSMB7 | Q99436 | 4/20 | 0.45 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10245784 | 0.89 | PSMB5 (0.64) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL12391075 | 0.89 | PSMB5 (0.64) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL30447218 | 0.84 | PSMB5 (0.65) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL19790242 | 0.83 | PSMB5 (0.52) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL12225907 | 0.79 | PSMB5 (0.81) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL25253176 | 0.76 | PSMB5 (0.49) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| Hydrochloric Acid SCHEMBL25253175 | 0.76 | PSMB5 (0.49) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| Hydrochloric Acid SCHEMBL25219917 | 0.76 | PSMB5 (0.49) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL24214122 | 0.76 | PSMB5 (0.59) | PSMB5PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL31664468 | 0.75 | PSMB5 (0.50) | PSMB5F2PRSS1F10F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552216-B1 | DERIVATIVES OF 1-AMINO-2-CYCLOPROPYLETHYLBORONIC ACID | MILLENNIUM PHARM INC (US) | 2018-01-24 | — | — | EP | disclosed |