Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195967 | 0.89 | SLC2A1 (0.50) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| SCHEMBL11080613 | 0.88 | TAAR1 (0.51) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| SCHEMBL4511086 | 0.86 | AOC3 (0.50) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| SCHEMBL21507667 | 0.86 | AOC3 (0.50) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| SCHEMBL17976247 | 0.86 | AOC3 (0.53) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| SCHEMBL355086 | 0.86 | AOC3 (0.53) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| SCHEMBL14312520 | 0.86 | AOC3 (0.53) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| SCHEMBL24527630 | 0.85 | AOC3 (0.53) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| SCHEMBL382558 | 0.85 | AOC3 (0.53) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL4935607 | 0.84 | AOC3 (0.51) | AOC3L3MBTL1TAAR1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272749-A1 | AMINO-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | Bayer Pharma Aktiengesellschaft (DE) | 2018-01-24 | — | — | EP | disclosed |