SCHEMBL1979297

SCHEMBL1979297

O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(=O)ON2C(=O)CC(S(=O)(=O)O)C2=O)N1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.58
MEN1 O00255 1/20 0.54
ABL1 P00519 1/20 0.54
LMNA P02545 1/20 0.54
PKM P14618 1/20 0.54
IDE P14735 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
RIN1 Q13671 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HLCS P50747 6/20 0.47
CA12 O43570 7/20 0.47
CA1 P00915 7/20 0.47
CA2 P00918 7/20 0.47
CA9 Q16790 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14417216 1.00 TDP1 (0.58) TDP1MEN1ABL1LMNAPKM
SCHEMBL17385535 1.00 TDP1 (0.58) TDP1MEN1ABL1LMNAPKM
SCHEMBL1549117 0.99 TDP1 (0.57) TDP1MEN1ABL1LMNAPKM
SCHEMBL4455260 0.92 TDP1 (0.55) TDP1MEN1ABL1LMNAPKM
SCHEMBL18780618 0.92 TDP1 (0.55) TDP1MEN1ABL1LMNAPKM
SCHEMBL6033324 0.92 TDP1 (0.55) TDP1MEN1ABL1LMNAPKM
SCHEMBL14417100 0.92 TDP1 (0.55) TDP1MEN1ABL1LMNAPKM
SCHEMBL12569327 0.92 TDP1 (0.55) TDP1MEN1ABL1LMNAPKM
SCHEMBL179912 0.92 TDP1 (0.55) TDP1MEN1ABL1LMNAPKM
SCHEMBL20740940 0.92 TDP1 (0.58) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100190257-A1 Self-Assembly of a Cell-Microparticle Hybrid THE UNIVERSITY OF IOWA RESEARCH FOUNDATION 2010-07-29 US claimed
EP-4717780-A2 QUANTITATIVE MASSIVELY PARALLEL PROTEOMICS Verily Life Sciences LLC (US) 2026-04-01 EP disclosed
EP-3488239-B1 QUANTITATIVE MASSIVELY PARALLEL PROTEOMICS VERILY LIFE SCIENCES LLC (US) 2026-03-25 EP disclosed
US-20250199011-A1 QUANTITATIVE MASSIVELY PARALLEL PROTEOMICS VERILY LIFE SCIENCES LLC (US) 2025-06-19 US disclosed
CN-119998887-A Methods and systems for predicting HLA epitopes 百欧恩泰美国公司 2025-05-13 CN disclosed
CN-113382750-B CDCP1 targeted therapy 贝斯以色列女执事医疗中心 2025-05-09 CN disclosed
CN-119864090-A Methods and systems for predicting HLA class II specific epitopes and characterizing CD4+ T cells 百欧恩泰美国公司 2025-04-22 CN disclosed
CN-119768425-A Anti-TL 1A antibodies and methods of use thereof 辉瑞大药厂 2025-04-04 CN disclosed
CN-119698427-A Methods and systems for predicting HLA class II specific epitopes and characterizing CD4+ T cells 百欧恩泰美国公司 2025-03-25 CN disclosed
US-12203939-B2 Quantitative massively parallel proteomics VERILY LIFE SCIENCES LLC (US) 2025-01-21 US disclosed
WO-2000002575-A1 PRION PROTEIN AND USES THEREOF V.I. TECHNOLOGIES, INC. (US) 2000-01-20 WO disclosed
EP-0920623-A1 BORON NEUTRON CAPTURE THERAPY USING PRE-TARGETING METHODS Immunomedics, Inc. (US) 1999-06-09 EP disclosed
US-5846741-A Boron neutron capture therapy using pre-targeting methods IMMUNOMEDICS, INC. (US) 1998-12-08 US disclosed
US-5821061-A REACTING A LIGAND IN A SAMPLE WITH A SUBSTANCE BONDED WITH A BACILLUS ALKALINE PHOSPHATASE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1998-10-13 US disclosed
US-5821095-A DETECTING A LIGAND IN SAMPLE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1998-10-13 US disclosed
WO-1998004917-A1 BORON NEUTRON CAPTURE THERAPY USING PRE-TARGETING METHODS IMMUNOMEDICS INC. (US) 1998-02-05 WO disclosed
EP-0724015-A2 Novel alkaline phosphatase, its production and use TOYO BOSEKI KABUSHIKI KAISHA (JP) 1996-07-31 EP disclosed
EP-0172153-B1 POLYNUCLEOTIDE HYBRIDIZATION PROBES SMITHKLINE BECKMAN CORPORATION (US) 1989-08-09 EP disclosed
US-4840892-A Polynucleotide hybridization probes SMITHKLINE BECKMAN CORPORATION (US) 1989-06-20 US disclosed
EP-0172153-A1 Polynucleotide hybridization probes SMITHKLINE BECKMAN CORPORATION (US) 1986-02-19 EP disclosed