Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.45 |
| ▸ | IKBKB | O14920 | 13/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12597811 | 0.93 | IKBKB (0.41) | SUV39H2IKBKBCHEK2METCHUK | |
| SCHEMBL3725168 | 0.92 | SUV39H2 (0.46) | SUV39H2IKBKBCHEK2METCHUK | |
| SCHEMBL1980453 | 0.88 | SUV39H2 (0.43) | SUV39H2IKBKBCHEK2METCHUK | |
| SCHEMBL12597421 | 0.85 | IKBKB (0.44) | SUV39H2IKBKBCHEK2METCHUK | |
| SCHEMBL473674 | 0.85 | IKBKB (0.40) | SUV39H2IKBKBCHEK2METCHUK | |
| SCHEMBL473788 | 0.85 | IKBKB (0.43) | SUV39H2IKBKBCHEK2METCHUK | |
| SCHEMBL3723523 | 0.85 | IKBKB (0.43) | SUV39H2IKBKBCHEK2METCHUK | |
| SCHEMBL11908837 | 0.85 | SUV39H2 (0.44) | SUV39H2IKBKBCHEK2METCHUK | |
| SCHEMBL12597220 | 0.83 | TLR7 (0.41) | IGF1R | |
| SCHEMBL3723610 | 0.83 | HDAC4 (0.42) | SUV39H2IKBKBCHEK2METCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070299-A1 | TRI-SUBSTITUTED 9H-BETA-CARBOLINE (OR 9H-PYRIDO[3,4-B]INDOLE) DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | disclosed |