Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134884 | 0.87 | CYP1A2 (0.85) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL36762 | 0.87 | HSD17B10 (1.00) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL29357214 | 0.87 | HSD17B10 (1.00) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL5194597 | 0.84 | HSD17B10 (0.79) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| 1-Naphthol SCHEMBL9575454 | 0.84 | CYP1A2 (0.85) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL1397170 | 0.83 | IDO1 (0.65) | HSD17B10CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL29357437 | 0.83 | IDO1 (0.65) | HSD17B10CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL23499944 | 0.82 | CYP1A2 (0.75) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL29625648 | 0.82 | CYP1A2 (0.75) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL17553393 | 0.81 | HSD17B10 (0.72) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011069846-A1 | LOW-VISCOSITY EPOXY RESIN COMPOSITION WITH LOW BLUSHING | SIKA TECHNOLOGY AG (CH) | 2011-06-16 | — | — | WO | disclosed |