Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 20/20 | 0.81 |
| ▸ | CCR5 | P51681 | 1/20 | 0.77 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.77 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186577 | 0.94 | CCR4 (0.81) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL185591 | 0.91 | CCR4 (0.80) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL356109 | 0.90 | CCR4 (0.79) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL357889 | 0.90 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL358836 | 0.89 | CCR4 (0.78) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL357417 | 0.89 | CCR4 (0.78) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL356901 | 0.89 | CCR4 (0.87) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL357403 | 0.89 | CCR4 (0.91) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL358085 | 0.89 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL356665 | 0.88 | CCR4 (0.81) | CCR4CCR5FFAR4SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025474-A1 | INDAZOLE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | WO | disclosed |