Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967594 | 0.84 | EGLN1 (0.67) | EGLN2EGLN1BBOX1THRATHRB | |
| SCHEMBL1973105 | 0.83 | SCN9A (0.42) | EGLN2EGLN1BBOX1THRATHRB | |
| SCHEMBL969347 | 0.76 | EGLN1 (0.67) | EGLN2EGLN1BBOX1THRATHRB | |
| SCHEMBL1976686 | 0.75 | SCN9A (0.42) | EGLN2EGLN1BBOX1THRATHRB | |
| SCHEMBL1974153 | 0.74 | POLB (0.42) | EGLN2EGLN1BBOX1THRATHRB | |
| SCHEMBL1977214 | 0.72 | EGLN1 (0.41) | EGLN2EGLN1BBOX1THRATHRB | |
| SCHEMBL1975813 | 0.69 | POLB (0.42) | EGLN2EGLN1PTPN1PTPRADHODH | |
| SCHEMBL1975055 | 0.68 | EGLN1 (0.41) | EGLN2EGLN1THRATHRBPTPN1 | |
| SCHEMBL14672078 | 0.68 | EGLN1 (0.71) | EGLN2EGLN1BBOX1THRATHRB | |
| SCHEMBL5316412 | 0.68 | EGLN1 (0.57) | EGLN2EGLN1BBOX1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866318-B1 | THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN INC (US) | 2011-06-22 | — | — | EP | claimed |