⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28163505 | 0.74 | — | — | |
| SCHEMBL27696601 | 0.74 | — | — | |
| SCHEMBL27861669 | 0.72 | — | — | |
| SCHEMBL283465 | 0.72 | — | — | |
| SCHEMBL5857957 | 0.72 | — | — | |
| SCHEMBL1637783 | 0.72 | — | — | |
| SCHEMBL3721406 | 0.70 | — | — | |
| SCHEMBL28660686 | 0.70 | — | — | |
| SCHEMBL6341539 | 0.70 | — | — | |
| SCHEMBL5153426 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110062761-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-05-13 | — | — | CN | claimed |
| EP-1495015-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | claimed |
| WO-2003087084-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | claimed |
| CN-118359638-A | Compound serving as RET kinase inhibitor and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-105683157-B | Sulfonamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-104479688-B | A kind of containing the liquid-crystal compounds of difluoro-methoxy bridged bond, compositions and application thereof | 北京八亿时空液晶科技股份有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-105683157-A | Sulfonamides as modulators of sodium channels | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-104498053-B | A kind of liquid-crystal compounds that contains difluoro-methoxy bridged bond, composition and application thereof | BEIJING BAYI SPACE LCD MATERIALS TECHNOLOGY CO., LTD. (CN) | 2016-05-11 | — | — | CN | disclosed |
| CN-105026373-A | Pyridone amides as sodium channel modulators | VERTEX PHARMA | 2015-11-04 | — | — | CN | disclosed |
| CN-104498053-A | Liquid crystal compound containing difluoromethoxy bridged bond, composition and application of liquid crystal compound | JIANG ZHANYING | 2015-04-08 | — | — | CN | disclosed |
| CN-104479688-A | Liquid crystal compound containing difluoromethoxy bridged bond, composition and application of liquid crystal compound | JIANG ZHANYING | 2015-04-01 | — | — | CN | disclosed |
| CN-102952112-A | Tricyclic guanidine derivatives as sodium-proton exchange inhibitors | NICHOLAS PIRAMAL INDIA LTD | 2013-03-06 | — | — | CN | disclosed |
| US-20120295920-A1 | 5-AMINO-4-HYDROXYPENTOYL AMIDES | JANSSEN SCIENCES IRELAND UC (IE) | 2012-11-22 | — | — | US | disclosed |
| EP-2509950-A1 | 5-AMINO- 4-HYDROXYPENTOYL AMIDES | Janssen R&D Ireland (IE) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070131-A1 | 5-AMINO- 4-HYDROXYPENTOYL AMIDES | TIBOTEC PHARMACEUTICALS (IE) | 2011-06-16 | — | — | WO | disclosed |
| CN-101981006-A | Cyclic indole-3-carboxamides, their preparation and their use as pharmaceuticals | SANOFI AVENTIS | 2011-02-23 | — | — | CN | disclosed |
| CN-101970437-A | Cyclic azaindole-3-carboxamides, their preparation and their use as pharmaceuticals | SANOFI AVENTIS | 2011-02-09 | — | — | CN | disclosed |
| CN-101627016-A | Compound (I) | SYNGENTA PARTICIPATIONS AG | 2010-01-13 | — | — | CN | disclosed |
| EP-1812420-A1 | TRICYCLIC GUANIDINE DERIVATIVES AS SODIUM-PROTON EXCHANGE INHIBITORS | Nicholas Piramal India Limited (IN) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006051476-A1 | TRICYCLIC GUANIDINE DERIVATIVES AS SODIUM-PROTON EXCHANGE INHIBITORS | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2006-05-18 | — | — | WO | disclosed |