Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15105941 | 0.88 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| SCHEMBL1982625 | 0.87 | CYP3A4 (0.39) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| Hydrochloric Acid SCHEMBL1440458 | 0.86 | CYP3A4 (0.39) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| SCHEMBL1745662 | 0.84 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| SCHEMBL1747170 | 0.84 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| SCHEMBL1747298 | 0.83 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| SCHEMBL1745953 | 0.83 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| SCHEMBL18727347 | 0.83 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| SCHEMBL16282782 | 0.83 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 | |
| SCHEMBL10192323 | 0.83 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP1A2CYP2D6NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152237-A1 | Chemical Compounds | GLAXOSMITHKLINE LLC | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152237-A1 | Chemical Compounds | SLC10A1, UGT1A3, UGT2B7 | CYP3A4 52/4885CYP2C9 40/4885CYP1A2 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.