SCHEMBL19804138

SCHEMBL19804138

C=C(C)C(=O)Oc1cc(CO)ccc1-c1ccc(C2CCCCC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 1/20 0.42
APP P05067 1/20 0.42
S1PR1 P21453 7/20 0.41
S1PR5 Q9H228 5/20 0.41
FFAR4 Q5NUL3 1/20 0.41
S1PR3 Q99500 4/20 0.40
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
NAAA Q02083 1/20 0.35
ASAH1 Q13510 1/20 0.35
PRKAB2 O43741 1/20 0.35
PRKAG1 P54619 1/20 0.35
PRKAA2 P54646 1/20 0.35
PRKAA1 Q13131 1/20 0.35
PRKAG3 Q9UGI9 1/20 0.35
PRKAG2 Q9UGJ0 1/20 0.35
PRKAB1 Q9Y478 1/20 0.35
S1PR4 O95977 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19804457 0.91 S1PR1 (0.43) CYP3A4CYP2C9APPS1PR1S1PR5
SCHEMBL19804537 0.89 S1PR1 (0.44) CYP3A4CYP2C9APPS1PR1S1PR5
SCHEMBL19804146 0.87 FFAR4 (0.41) CYP3A4CYP2C9APPS1PR1S1PR5
SCHEMBL19796799 0.83 CYP2C9 (0.38) CYP3A4CYP2C9FFAR4S1PR3CYP4F2
SCHEMBL19803289 0.83 FFAR4 (0.41) CYP3A4CYP2C9APPFFAR4GAA
SCHEMBL19804558 0.83 FFAR4 (0.43) CYP3A4CYP2C9APPS1PR1S1PR5
SCHEMBL19804418 0.81 CYP3A4 (0.40) CYP3A4CYP2C9APPS1PR1S1PR5
SCHEMBL19803994 0.81 CYP4F2 (0.44) S1PR1S1PR5FFAR4CYP4F2CYP4A11
SCHEMBL19804781 0.81 FFAR4 (0.40) CYP3A4CYP2C9APPS1PR1S1PR5
SCHEMBL19804768 0.80 CYP3A4 (0.48) CYP3A4CYP2C9APPS1PR1S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, C1S, AP3D1 CYP3A4 2192/4885CYP2C9 4202/4885APP 325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.