Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 16/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 16/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22636126 | 0.86 | KCNK3 (0.59) | KDM4EGAASLC2A1KCNK3KCNK9 | |
| SCHEMBL19807667 | 0.84 | KDM4E (0.62) | KDM4EGAASLC2A1KCNK3KCNK9 | |
| SCHEMBL29458055 | 0.84 | KCNK3 (0.67) | KDM4EGAASLC2A1KCNK3KCNK9 | |
| SCHEMBL22916200 | 0.84 | KDM4E (0.60) | KDM4EGAASLC2A1KCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL31448315 | 0.83 | KDM4E (0.59) | KDM4EGAASLC2A1KCNK3KCNK9 | |
| SCHEMBL29791139 | 0.83 | KCNK3 (0.60) | KDM4EGAASLC2A1KCNK3KCNK9 | |
| SCHEMBL19807787 | 0.82 | KCNK3 (0.76) | KCNK3KCNK9 | |
| SCHEMBL19807785 | 0.82 | KCNK3 (0.77) | KCNK3KCNK9 | |
| SCHEMBL19807662 | 0.81 | KDM4E (0.65) | KDM4EGAASLC2A1KCNK3KCNK9 | |
| SCHEMBL18963197 | 0.81 | KDM4E (0.75) | KDM4EGAASLC2A1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015196-A1 | SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | WO | disclosed |