Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 19/20 | 0.71 |
| ▸ | KCNK9 | Q9NPC2 | 19/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807652 | 0.88 | KCNK3 (0.59) | KCNK3KCNK9 | |
| SCHEMBL19807887 | 0.86 | KCNK3 (0.73) | KCNK3KCNK9KDM4E | |
| SCHEMBL22916216 | 0.85 | KCNK3 (0.74) | KCNK3KCNK9KDM4E | |
| SCHEMBL24208185 | 0.85 | KCNK3 (0.75) | KCNK3KCNK9 | |
| SCHEMBL19807885 | 0.84 | KCNK3 (0.75) | KCNK3KCNK9 | |
| SCHEMBL22916255 | 0.84 | KCNK3 (0.57) | KCNK3KCNK9KDM4E | |
| SCHEMBL19807884 | 0.83 | KCNK3 (0.76) | KCNK3KCNK9KDM4E | |
| SCHEMBL22916220 | 0.83 | KCNK3 (0.59) | KCNK3KCNK9KDM4E | |
| SCHEMBL19807801 | 0.83 | KCNK3 (0.58) | KCNK3KCNK9 | |
| SCHEMBL18963162 | 0.83 | KCNK3 (1.00) | KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015196-A1 | SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | WO | disclosed |