Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979556 | 0.93 | S1PR1 (0.50) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1488633 | 0.86 | S1PR1 (0.70) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1488771 | 0.83 | S1PR1 (0.59) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1489118 | 0.82 | S1PR1 (0.63) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1488651 | 0.82 | S1PR1 (0.60) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1488990 | 0.82 | S1PR1 (0.61) | S1PR1S1PR3S1PR4S1PR5LTA4H | |
| SCHEMBL1488735 | 0.82 | S1PR1 (0.71) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1979878 | 0.82 | S1PR1 (0.49) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1489136 | 0.81 | S1PR1 (0.60) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1488698 | 0.81 | S1PR1 (0.59) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343287-A1 | New 2-aminothiadiazole derivatives | Almirall, S.A. (ES) | 2011-07-13 | — | — | EP | claimed |
| EP-2343287-A1 | New 2-aminothiadiazole derivatives | Almirall, S.A. (ES) | 2011-07-13 | — | — | EP | disclosed |
| EP-2343287-A1 | New 2-aminothiadiazole derivatives | Almirall, S.A. (ES) | 2011-07-13 | — | — | EP | disclosed |
| WO-2011069647-A1 | NEW 2-AMINOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011069647-A1 | NEW 2-AMINOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-06-16 | — | — | WO | disclosed |