SCHEMBL198101

SCHEMBL198101

C=C[Si](C)(OCCCC)OCCCC

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
HPGD P15428 1/20 0.39
ALDH1A1 P00352 2/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
ATM Q13315 1/20 0.32
CYP3A4 P08684 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP19A1 P11511 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22077210 0.93 TSHR (0.36) TSHRHPGDALDH1A1
SCHEMBL5055527 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL22069510 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL2493357 0.91 TSHR (0.39) TSHRALDH1A1
SCHEMBL2001505 0.88 HPGD (0.32) TSHRHPGD
SCHEMBL1068409 0.85
SCHEMBL22661056 0.83
SCHEMBL2001503 0.82
SCHEMBL5616868 0.81 TSHR (0.41) TSHRALDH1A1ATMCYP3A4
SCHEMBL15302455 0.81 TSHR (0.39) TSHRHPGDALDH1A1ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230094797-A1 THERMALLY EXPANDABLE COMPOSITIONS WITH IMPROVED HUMIDITY STORAGE RESISTANCE SIKA TECHNOLOGY AG (CH) 2023-03-30 US claimed
EP-4103643-A1 THERMALLY EXPANDABLE COMPOSITIONS WITH IMPROVED HUMIDITY STORAGE RESISTANCE Sika Technology AG (CH) 2022-12-21 EP claimed
CN-115087693-A Thermally expandable compositions having improved moisture and gas storage resistance SIKA技术股份公司 2022-09-20 CN claimed
WO-2021160852-A1 THERMALLY EXPANDABLE COMPOSITIONS WITH IMPROVED HUMIDITY STORAGE RESISTANCE SIKA TECHNOLOGY AG (CH) 2021-08-19 WO claimed
EP-3865538-A1 THERMALLY EXPANDABLE COMPOSITIONS WITH IMPROVED HUMIDITY STORAGE RESISTANCE Sika Technology AG (CH) 2021-08-18 EP claimed
EP-2313443-B1 SILANE-MODIFIED POLYOLEFINS HAVING A HIGH DEGREE OF FUNCTIONALIZATION EVONIK DEGUSSA GMBH (DE) 2019-03-13 EP claimed
EP-3340253-A1 UV-RESISTANT ELECTRODE ASSEMBLY Solvay SA (BE) 2018-06-27 EP claimed
EP-3340252-A1 ELECTRODE ASSEMBLY Solvay SA (BE) 2018-06-27 EP claimed
EP-2196482-B1 Silane-grafted alpha-olefin-vinyl acetate copolymer containing crosslinkable silyl groups, process for the preparation thereof and use for the preparation of insulation or sheath materials for cables or lines ARLANXEO DEUTSCHLAND GMBH (DE) 2018-02-28 EP claimed
EP-2313267-B1 USE OF SILANE-MODIFIED PLYOLEFINS AS ADHESION PROMOTERS FOR THE PRODUCTION OF FLAT LAMINATES EVONIK DEGUSSA GMBH (DE) 2018-02-21 EP claimed
EP-1721731-A1 Layered structure, method of its preparation and use Celanese Emulsions GmbH (DE) 2006-11-15 EP claimed
EP-0827994-B1 Use of grafted amorphous poly-alfa-olefins as moisture-curable raw material for adhesives and as adhesives DEGUSSA (DE) 2002-12-18 EP claimed
JP-3094128-B2 2000-10-03 JP claimed
US-6114423-A Redispersable cross-linkable dispersion powders WACKER-CHEMIE GMBH (DE) 2000-09-05 US claimed
US-5994474-A Use of silane-grafted amorphous poly-α-olefins as moisture-crosslinking adhesive base material or adhesive HEULS AKTIENGESELLSCHAFT (DE) 1999-11-30 US claimed
EP-0840754-B1 REDISPERSABLE CROSS-LINKABLE DISPERSION POWDERS WACKER CHEMIE GMBH (DE) 1999-06-02 EP claimed
EP-0840754-A1 REDISPERSABLE CROSS-LINKABLE DISPERSION POWDERS Wacker-Chemie GmbH (DE) 1998-05-13 EP claimed
CN-1177623-A Use of silane-grafted amorphous poly-alpha olefins as moisture-crosslinking adhesive base material or adhesive HUELS CHEMISCHE WERKE AG (DE) 1998-04-01 CN claimed
EP-0827994-A2 Use of grafted amorphous poly-alfa-olefins as moisture-curable raw material for adhesives and as adhesives HÜLS AKTIENGESELLSCHAFT (DE) 1998-03-11 EP claimed
WO-1997004013-A1 REDISPERSABLE CROSS-LINKABLE DISPERSION POWDERS WACKER-CHEMIE GMBH (DE) 1997-02-06 WO claimed