Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541419 | 1.00 | TSHR (0.52) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL29750140 | 1.00 | TSHR (0.52) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL28311292 | 1.00 | TSHR (0.52) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL29750226 | 1.00 | TSHR (0.52) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL5491066 | 1.00 | TSHR (0.52) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11810800 | 0.97 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7166999 | 0.95 | TSHR (0.46) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL322056 | 0.95 | TSHR (0.58) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL29807605 | 0.95 | TSHR (0.58) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL599885 | 0.89 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604469-B2 | Method for the preparation of a partially hydrogenated polyacene and an intermediate thereof | FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) | 2020-03-31 | — | — | US | claimed |
| US-20190161426-A1 | METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF | UNIVERSITAT ROVIRA I VIRGILI (ES) | 2019-05-30 | — | — | US | claimed |
| WO-2018019436-A1 | METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2018-02-01 | — | — | WO | claimed |
| EP-3275876-A1 | METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF | Fundació Institut Català D'investigació Quimica (ES) | 2018-01-31 | — | — | EP | claimed |
| US-10604469-B2 | Method for the preparation of a partially hydrogenated polyacene and an intermediate thereof | FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) | 2020-03-31 | — | — | US | disclosed |
| US-20190161426-A1 | METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF | UNIVERSITAT ROVIRA I VIRGILI (ES) | 2019-05-30 | — | — | US | disclosed |
| WO-2018019436-A1 | METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2018-02-01 | — | — | WO | disclosed |
| EP-3275876-A1 | METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF | Fundació Institut Català D'investigació Quimica (ES) | 2018-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604469-B2 | Method for the preparation of a partially hydrogenated polyacene and an intermediate thereof | PARN, PCBP1, PARG | TSHR 4466/4885MEN1 973/4885KMT2A 528/4885 |
| US-20190161426-A1 | METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF | PARN, PCBP1, PARG | TSHR 4466/4885MEN1 973/4885KMT2A 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.