Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812517 | 1.00 | PTGER4 (0.54) | PTGER4PTGER2PTGER3PTGER1LTB4R | |
| SCHEMBL344776 | 0.86 | PTGER4 (0.70) | PTGER4PTGER2PTGER3PTGER1LTB4R | |
| SCHEMBL344775 | 0.86 | PTGER4 (0.70) | PTGER4PTGER2PTGER3PTGER1LTB4R | |
| SCHEMBL9198695 | 0.84 | HDAC8 (0.56) | PTGER4PTGER2PTGER3PTGER1LTB4R | |
| SCHEMBL9198688 | 0.84 | HDAC8 (0.56) | PTGER4PTGER2PTGER3PTGER1LTB4R | |
| SCHEMBL344658 | 0.83 | PTGER3 (0.68) | PTGER4PTGER2PTGER3PTGER1LTB4R | |
| SCHEMBL344657 | 0.83 | PTGER3 (0.68) | PTGER4PTGER2PTGER3PTGER1LTB4R | |
| SCHEMBL344708 | 0.82 | BACE1 (0.54) | KDM4EAKR1C3ALDH1A1PKMPTPN1 | |
| SCHEMBL344709 | 0.82 | BACE1 (0.54) | KDM4EAKR1C3ALDH1A1PKMPTPN1 | |
| SCHEMBL344621 | 0.82 | AKR1C3 (0.52) | KDM4ELMNAAKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028484-A1 | Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Rosacea | AmDerma Pharmaceuticals, LLC | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028484-A1 | Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Rosacea | CYP8B1, CYP1B1, CYP26B1 | PTGER4 2517/4885PTGER2 1503/4885PTGER3 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.