Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935918 | 0.87 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL4288502 | 0.86 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL19097419 | 0.84 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL4295999 | 0.84 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL21024180 | 0.83 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL13977697 | 0.82 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL4282902 | 0.82 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL4290118 | 0.82 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL14935781 | 0.82 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL14936024 | 0.82 | TRPV1 (0.43) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9878991-B2 | TRPV1 antagonists including dihydroxy substituent and uses thereof | PURDUE PHARMA L.P. (US) | 2018-01-30 | — | — | US | disclosed |