Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GLP1R | P43220 | 8/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SELL | P14151 | 3/20 | 0.39 |
| ▸ | SELP | P16109 | 3/20 | 0.39 |
| ▸ | SELE | P16581 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286536 | 1.00 | MAPK1 (0.51) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL21226768 | 1.00 | MAPK1 (0.51) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL19480776 | 1.00 | MAPK1 (0.51) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL19608855 | 1.00 | MAPK1 (0.51) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL21017006 | 0.97 | GLP1R (0.49) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL17519197 | 0.96 | MAPK1 (0.56) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL19820023 | 0.96 | MAPK1 (0.56) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL25775135 | 0.96 | MAPK1 (0.56) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL20285786 | 0.94 | ESR1 (0.49) | MAPK1GLP1RESR1PGRHTR1A | |
| SCHEMBL18611008 | 0.93 | MAPK1 (0.47) | MAPK1GLP1RESR1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9879265-B2 | Oligonucleotide conjugates | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2018-01-30 | — | — | US | disclosed |