Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24996409 | 0.87 | TYK2 (0.34) | — | |
| SCHEMBL10139171 | 0.75 | DYRK1A (0.32) | — | |
| SCHEMBL12396387 | 0.71 | ADORA2A (0.34) | — | |
| SCHEMBL2739652 | 0.66 | DYRK1A (0.53) | JAK2 | |
| SCHEMBL14104385 | 0.65 | MAPK1 (0.41) | — | |
| SCHEMBL25549142 | 0.65 | TYK2 (0.36) | — | |
| SCHEMBL18711832 | 0.64 | TYK2 (0.41) | — | |
| SCHEMBL19820315 | 0.61 | HRH4 (0.34) | JAK2 | |
| SCHEMBL24996725 | 0.61 | AAK1 (0.36) | — | |
| SCHEMBL22693058 | 0.61 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9879028-B2 | Compounds that modulate EGFR activity and methods for treating or preventing conditions therewith | Gatekeeper Pharmaceuticals, Inc. (US) | 2018-01-30 | — | — | US | disclosed |